"[30], InChI=1S/C7H6O2.Na/c8-7(9)6-4-2-1-3-5-6;/h1-5H,(H,8,9);/q;+1/p-1, InChI=1/C7H6O2.Na/c8-7(9)6-4-2-1-3-5-6;/h1-5H,(H,8,9);/q;+1/p-1, Except where otherwise noted, data are given for materials in their, "International Programme on Chemical Safety", "Skin Deep® Cosmetics Database | Environmental Working Group", "Suggested guidelines for the diagnosis and management of urea cycle disorders", Add-on Treatment of Benzoate for Schizophrenia A Randomized, Double-blind, Placebo-Controlled Trial of d-Amino Acid Oxidase Inhibitor, Mental Health Research Institute Staff Publications, "Cinnamon May Help Halt Parkinson's Disease Progression - News Releases - Rush University Medical Center", mayoclinic.org, Caffeine And Sodium Benzoate (Injection Route), ebi.ac.uk, CHEBI:32140 - sodium caffeine benzoate, "Studies on the mechanism of the antifungal action of benzoate", "CFR - Code of Federal Regulations Title 21", "Concise International Chemical Assessment Document 26: Benzoic acid and sodium benzoate", "Final Report on the Safety Assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate", "Data on Benzene in Soft Drinks and Other Beverages", United States Food and Drug Administration, Food Standards Agency issues revised advice on certain artificial colours, Agency revises advice on certain artificial colours, The United States Pharmacopeial Convention, International Programme on Chemical Safety - Benzoic Acid and Sodium Benzoate report, "Dose-dependent pharmacokinetics of benzoic acid following oral administration of sodium benzoate to humans", 2008 United States salmonellosis outbreak, 2017–18 South African listeriosis outbreak, 2018 Australian rockmelon listeriosis outbreak, Spanish Agency for Food Safety and Nutrition, https://en.wikipedia.org/w/index.php?title=Sodium_benzoate&oldid=982153065, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License, This page was last edited on 6 October 2020, at 13:19.

Canadian Environmental Protection Act (CEPA) Environmental Registry. Evidence for human carcinogenicity based on 1986 guidelines. Lastly, protecting products from light or heat exposure can limit the chances of benzene formation. Data on Benzene in Soft Drinks and other Beverages. CIR (Cosmetic Ingredient Review).

Sodium benzoate is used as a preservative in some over-the-counter and prescription medications, particularly in liquid medicines like cough syrup. Other sources include seafood and dairy products like milk, cheese, and yogurt. This is because there are ways of formulating products that can prevent this reaction from occurring. It will easily dissolve in water, forming a transpare… Sodium benzoate is a preservative commonly used in foods, pharmaceuticals and cosmetics. Washington DC. antimicrobial preservative and flavoring agent used in the food industry and a tablet and capsule lubricant used in the pharmaceutical manufacturing industry Sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. The U.S. Food and Drug Administration (FDA) specifies a maximum level of 0.1 percent of sodium benzoate in food and at this level sodium benzoate is generally recognized as safe by the FDA.

Preliminary studies raise questions about its safety, but more research is needed. Sodium lauryl sulfate (SLS) is found in shampoos, soaps, various beauty and cleaning products, and even some foods. Benzoic acid has good anti-microbial features but does not dissolve well in water, whereas sodium benzoate dissolves very well in water. Sodium benzoate is produced by the neutralization of benzoic acid,[3] which is itself produced commercially by partial oxidation of toluene with oxygen. 2008. Recent research shows that sodium benzoate may be beneficial as an add-on therapy (1 gram/day) in schizophrenia. Sodium benzoate inhibits the growth of potentially harmful bacteria, mold, and other microbes in food, thus deterring spoilage. Other factors, including exposure to heat and light, as well as longer storage periods, can increase benzene levels (9). It has a role as an antimicrobial food preservative, a drug allergen, an EC 1.13.11.33 ( arachidonate 15-lipoxygenase) inhibitor, an EC 3.1.1.3 (triacylglycerol lipase) inhibitor, an algal metabolite, a human xenobiotic metabolite and a plant metabolite. 12 Common Food Additives — Should You Avoid Them? It is important to note that research is preliminary, and no human research has been conducted. Both benzoic acid and sodium benzoate occur naturally in many foods. Both benzoic acid and sodium benzoate occur naturally in many foods. In combination with ascorbic acid (vitamin C, E300), sodium benzoate and potassium benzoate may form benzene. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Sodium benzoate is a preservative in food, also known as E211. Cancer . Food Additive Status List. A study conducted at Sheffield University in the UK in the field of molecular biology and biotechnology found that sodium benzoate increases the production of free radicals. Domestic Substances List Categorization.

Learn more | Legal Disclaimer, Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. EC (Environment Canada). Learn more about this chemical…. Sodium benzoate, along with phenylbutyrate, is used to treat hyperammonemia.

In this study, sodium benzoate appeared to attack the mitochondria of cells, damaging their ability to prevent oxygen leaks that create free radicals. Our website services, content, and products are for informational purposes only. Look for … Sodium benzoate is used in acidic foods and products to control bacteria, mould, yeasts, and other microbes. Environmental Working Group.

Consult a doctor for appropriate testing if you suspect you have an allergy to sodium benzoate (2). A study conducted at. Ammonia is a byproduct of protein breakdown, and blood levels may become dangerously high in certain medical conditions (2). Additionally, medicinal doses of sodium benzoate may deplete your body of the amino acid carnitine, which plays a critical role in energy production. Sodium benzoate medicine can be used to treat high blood ammonia levels. Aside from its use in processed foods and beverages, sodium benzoate is also added to some medicines, cosmetics, personal care products, and industrial products. Sodium benzoate is a preservative commonly used in foods, pharmaceuticals and cosmetics. So is the presence of sodium benzoate and vitamin C in a skincare product a major concern? Because Sodium Benzoate only converts to benzoic acid in acidic environments, it is not used for its anti-microbial action unless the pH is below about 3.6. , benzene-induced cancer in humans was first reported in the late 1920s.



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